Sources tell NY1 that the EPA plans to designate it a superfund site during a conference call on Monday.
In 2008, the EPA agreed to test the amount of toxic chemicals and hazardous waste in the creek, to determine whether it should be a superfund site.
The designation would make it eligible for federal funding to cover most of the costs.
The creek, which borders Brooklyn and Queens, was the site of a massive underground oil spill believed to have started in the 1950s that went unnoticed until 1978.