On an average day, the Animal Care Centers of New York City receives 40 to 60 animals.

But over Memorial Day weekend, that number skyrocketed to more than 300 homeless animals in four days. That includes every furry friend from dogs to cats to rabbits.

The flood of pets has left the organization's five centers in Manhattan, Brooklyn, and Staten Island overcrowded and its staff overextended.

"This stresses every department out," said Rita Viola, a placement supervisor at the Manhattan center. "With an increase in population, it really, unfortunately, doesn't allow us to care for the animals as high of quality as we would like."

The ACC is a nonprofit facility, contracted with the health department to run city animal shelters.

The organization says the uptick in surrendered animals has to do more with litters being born in the spring, rather than a rise in abandoned pets.

But ACC officials said with its policy of not turning animals away, and a 93 percent placement rate, the organization is desperate to find owners for all of the animals.

"We are New York City's only open admission shelter, so we cannot say no. We have a responsibility to this city, to this community to help both animals and people," Viola said. "We will take everybody. And yes, that does put — particularly during baby critter season — it does put a lot of the stress on our team."

Viola said the ACC has not received any dogs that contracted the dog influenza strain, the H3N2 virus, which has spread quickly through Brooklyn and now is into Manhattan.