An off-duty police officer accused of shooting a man to death during a road rage incident was hit with criminal charges Monday.

Officer Wayne Isaacs faces second degree murder charges for the fatal shooting of Delrawn Small on July 4.

Small was unarmed, but police initially said he punched Isaacs through his window several times before the shooting.

Surveillance video shows Small walking up to Isaacs car window, then immediately getting shot.

This is the first case Attorney General Eric Schneiderman has brought since Gov. Andrew Cuomo appointed his office to act as an independent prosecutor in police-involved shootings.

Small's wife said she is relieved Isaacs is facing criminal charges, while her lawyer said he is confident that the correct office is bringing the case.

"I want justice for my husband, Delrawn Small," Wenona Small said. "I want Officer Wayne Isaacs to spend the rest of his life in jail, and I will be at every court proceeding and hearing until there's justice for my husband."

"Certainly, the fact that an indictment has been secured for murder demonstrates that this new system works," attorney Sanford Rubenstein said.

Isaacs has been suspended from the NYPD without pay.

Small's family has filed a $25 million lawsuit against the city police department.