Jury selection is scheduled to begin Wednesday in a second trial for the former Manhattan bouncer accused of raping and killing 24-year-old Imette St. Guillen back in 2006. NY1's Lily Jamali filed the following report.

Imette St. Guillen was 24 years old and pursuing a graduate degree in criminal justice studies when she disappeared from a Manhattan bar late one night back in February 2006.

Many hours later, her body was found dumped in a lot in East New York. She'd been brutally assaulted, her hands and feet bound.

The Brooklyn District Attorney says 44-year-old Darryl Littlejohn abducted and killed her that night.

In the three years since, Littlejohn has been convicted of kidnapping and assaulting another woman -- a crime that already has him spending 25 years to life behind bars.

His trial on first degree murder charges in St. Guillen's death is set to begin.

His attorney says she's ready and has been pouring over documents for the last several months, working up the defense.

"It's been a long time for him as well. I think he's anxious to get going," said Defense Attorney Joyce David.

The last time anyone but her killer saw St. Guillen alive was at The Falls, a bar in SoHo where Littlejohn worked as a bouncer.

While the Brooklyn DA declined to comment on the upcoming trial, in the past Charles Hynes has called the DNA evidence "overwhelming."

Investigators say items that link Littlejohn to St. Guillen that night include plastic ties used to tie her up, a quilt in which her body was wrapped, and a snow brush found beneath her body. But Littlejohn's lawyer argues the evidence has been compromised.

"The evidence itself, the plastic ties, the quilt, the snow brush, were moved from lab to lab. They were transported by detectives involved in the case. At any point in time the evidence could have been tampered with," said David.

It's a claim the police department vehemently disputes.

The defense also plans to implicate the owner of The Falls, Daniel Dorrian, who she says held up the investigation by lying to police.

Dorrian's lawyer didn't return NY1's calls and The Falls has since shut down.

Activist Jeff Ragsdale helped move for changes to the city's nightlife regulations after the death of St. Guillen.

"If you lose a daughter to a brutal crime like this, there is never closure. That's why the New York nightlife scene put in more laws into motion to prevent this from happening with security cameras and background checks of bouncers. It should have been done way before this and a beautiful person died because of this," said Ragsdale.

The St. Guillen family lawyer says Imette's mother and sister will come to New York from their home in Boston for parts of the trial, which is expected to last about a month.