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New Yorkers first learned about Jasmina Anema's plight a few months ago, when family and supporters were trying to find a bone marrow donor for the six-year-old Harlem girl. Celebrities joined in the effort and more than 10,000 people offered their help.

Two near-perfect matches were found. One was used for a transplant, which at first seemed to be a success. But Anema has suffered a number of setbacks.

"We were a month ago so happy, everything was going back to normal. Life was going to be great again," said Theodora Anema, Jasmina's mother. "We tackled the disease, so I thought."

Then the Anemas received the bad news that Jasmina's leukemia is back and it's quickly getting worse.

"I knew I was to expect a relapse after some point but of course you think two years, five years, 10 years. Nobody expected this to happen so fast," said Theodora Anema. "The uncertainty of where it's going to go from here is nerve-wracking, heartbreaking, but we keep hoping."

Jasmina Anema's doctor would not speak with NY1, citing patient confidentiality.

But Theodora Anema says she's been told there are few options left. She says the doctor recommended an experimental gene therapy designed to slow down the spread of cancer cells, but the procedure has never been used on children.

"He suggested that we try this new treatment so we are going to go for that, and if that proves to be correct it will be a miracle," she said. "But we don't know yet when the right time is to start that."

In the meantime, Jasmina Anema and her mother continue to remain in good spirits.

"As you can see in the background, she plays with her iPhone, she plays Wii, she plays on the computer," said Theodora Anema. "She does all kinds of stuff."

While the ailing girl is not entirely aware of the grim outlook, her mother is fully aware of the tough road ahead.